Two rivers, the Trent and the Neuse, meet in North Carolina’s second oldest town and its former capital, a confluence that is an apt metaphor for a friendly little city where locals like to stroll, dine, shop and, well, meet up. New Bern is named for the capital of landlocked Switzerland, an odd choice in that the city is almost waterlocked. The historic district does feature architecture of a distinctively European styling, but New Bern can boast of its all-American bona fides: A city pharmacist formulated Pepsi Cola at his New Bern soda fountain in the 1890s. Greenville, NC, is inland, just up Highway 17 from New Bern, but it to is defined very much by water, in this case the Pamlico River, which flows from the sound of the same name. Cypress Landing, in Chocowinity, sits alongside the river and combines the golf and boating lifestyle into one reasonably priced package. And for those concerned about medical facilities, Greenville's medical campus rivals those of cities five times larger.